Graduate Institute Geneva The debate on drug policy reform has gained momentum in the last few years to reduce the harm caused by drugs through health- and human rights-based approaches. Innovative initiatives in relation to harm reduction, criminal justice reform, and drugs regulation are being explored and implemented at the local level in different countries. What are the implications of a bottom-up approach to drug policy reform? How do these strategies inform the debate at the global level? How can a coherent, multisectoral approach be fostered? These and other questions will be addressed in a dialogue session with Ethan Nadelmann, Founder and Executive Director of the Drug Policy Alliance, organised by the Global Health Centre at the Graduate Institute and Groupement Romand d'Etudes des Addictions.