04.04.2024

Key component found for malaria invasion

New Discovery Unravels Malaria Invasion Mechanism
Malaria-infected red blood cells. Photo: Swiss TPH/ AdobeStock

Swiss TPH "A recent breakthrough sheds light on how the malaria parasite, Plasmodium falciparum, invades human red blood cells. The study, led by the Swiss Tropical and Public Health Institute (Swiss TPH) and Griffith University’s Institute for Glycomics, reveals the role of a sugar called sialic acid in this invasion process. The findings, published yesterday in Cell Reports, have major implications for malaria vaccine and drug development. With 249 million cases of malaria and 608,000 deaths in 2022, malaria has remained an intractable global health threat. The malaria parasite Plasmodium falciparum is the leading cause of severe malaria and is responsible for the largest portion of malaria deaths."